J Haem Pract 2015; 2(2):20-21. doi: 10.17225/jhp00055
Consultant Obstetrician and Gynaecologist
Royal Free Hospital,
Pond St, London NW3 2QG, UK.
The issue of women with bleeding disorders was first reported by Professor von Willebrand in 1926, but it is only from around the mid 1990s that the issue has been fully recognised. Much of this is due to the vision and hard work of Professor Christine Lee and colleagues at the Katharine Dormandy Haemophilia Centre. This work has led to better diagnosis, better quality care and improved quality of life for women with bleeding disorders.
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Kadir RA, Economides DL, Sabin CA, et al. Frequency of inherited bleeding disorders in women with menorrhagia. Lancet 1998; 351: 485-9
Shankar M, Lee CA, Sabin CA, et al. von Willebrand disease in women with menorrhagia: a systematic review. BJOG 2004; 111(7): 734-40.
Chi C, Lee CA, England A, et al. Obstetric analgesia and anaesthesia in women with inherited bleeding disorders. Thromb Haemost 2009; 101(6): 1104-11.
Chi C, Shiltagh N, Kingman CEC, et al. Identification and management of women with inherited bleeding disorders: a survey of obstetricians and gynaecologists in the United Kingdom. Haemophilia 2006; 12(4): 405–412.
Dilley A, Drews C, Lally C, et al. A survey of gynecologists concerning menorrhagia: perceptions of bleeding disorders as a possible cause. J Womens Health Gend Based Med. 2002; 11(1): 39-44.
Lee CA, Chi C, Pavord SR, et al. The obstetric and gynaecological management of women with inherited bleeding disorders--review with guidelines produced by a taskforce of UK Haemophilia Centre Doctors’ Organization. Haemophilia 2006; 12(4):301-36.
Lee CA, Chi C, Shiltagh N, et al. Review of a multidisciplinary clinic for women with inherited bleeding disorders. Haemophilia 2009; 15(1): 359-60. doi: 10.1111/j.1365-2516.2008.01824.x.
Chi C, Lee CA, Shiltagh N, et al. Pregnancy in carriers of haemophilia. Haemophilia 2008; 14(1): 56-64.
Chi C, Hyett JA, Finning KM, et al. Non-invasive first trimester determination of fetal gender: a new approach for prenatal diagnosis of haemophilia. BJOG 2006; 113(2): 239-42.
Tsui NBY, Kadir RA, Chan KCA, et al. Noninvasive prenatal diagnosis of hemophilia by microfluidics digital PCR analysis of maternal plasma DNA. Blood 2011; 117(13):3684-91.